Ketamine was discovered to be an effective antidepressant in the late 1990s. Since then, decades have passed, and its use has grown significantly. Ketamine has proven to be a safe and effective treatment for depression and anxiety as well as other conditions like PTSD, bi-polar disorder, and even some chronic pain conditions. This leads many providers and patients to agree that ketamine is the most effective depression treatment available.
If you are still curious if ketamine is safe, or if it is addictive, then read on to learn more about this wonderful treatment. If you have any other questions, please feel free to reach out to us and let us know what you think.
In the 1960’s ketamine was FDA approved as a dissociative anesthetic and analgesic. Due to its efficacy in various applications, it has since earned a spot on the World Health Organization’s list of essential medicines. As an antidepressant, treatment dosage is too low to produce any anesthetic effects. When used correctly, ketamine is highly effective at treating even the worst cases of depression, oftentimes when other treatments fail.
We have found that administering ketamine intravenously is the most effective delivery method. As an infusion, the solution is 100% biologically available allowing for the greatest chance of a successful treatment. We can also be offered it intranasally, intramuscularly, orally, or sublingually however these methods offer less of the medication to the body as they pass through to the brain.
As with most medications, ketamine can be abused in large doses recreationally. This is largely how it earned its undeserved reputation as a “party drug.” Despite this, ketamine is not a physically addictive substance. When used as a depression treatment, the ketamine is administered in much smaller doses. This also prevents most, if not all, of the typical side-effects from taking a larger dose. Each treatment is only administered in our clinic, and we do not send our patients home with prescriptions for ketamine.
Ketamine has been shown to offer effective symptom relief in over 70% patients — most of the time after the first infusion. Considering that traditional antidepressants have a 40% success rate, and take weeks or months to have an effect, this is a remakable difference. Each patient’s body and mind is different, so that means each recipient will experience different results. Some patients feel an immediate shift in their attitude and mood for the better, while others feel their fog of depression lift gradually. With such a high success rate, and relatively low risk, we are confident that most patients will find relief in a predicable amount of time.
All patients should continue their regular medications and follow any instructions given by their doctors. Each patients medications are reviewed before receiving any infusions to insure there are no contraindications between them and ketamine.
Ketamine is not physically addictive. However, like most drugs, when abused recreationally in large doses, it can become psychologically addictive. When ketamine is administered for depression it is done so in safer, smaller doses. Since ketamine infusions can only be administered under supervision in an official clinic like ours, there is a relatively low risk involved for each patient. Our patients are never given prescriptions for ketamine, nor can any patient leave with it.
Numerous studies have found ketamine infusions to be most effective when they are administered serially over a two week period. We recommend a set of 4-6 infusions initially, followed by occasional maintenance infusions as needed. For some maintenance infusions will only few times a year, while for others it may be more frequent than that.
Ketamine works where other depression treatments fail, alleviating symptoms in up to 70% of patients…including those who have failed to find relief through traditional first-line depression treatments such as talk therapy and antidepressant medications.
Where antidepressants can take up to three months to begin alleviating symptoms, ketamine begins working right away, oftentimes providing symptomatic relief after just 1-2 infusions.
Contrary to popular belief, ketamine is not a physically addictive substance. Furthermore, ketamine infusions are administered in a ketamine clinic, under close medical supervision, preventing the medication from making its way into the wrong hands where it could be misused.